https://idr.niser.ac.in/jspui/handle/123456789/21 Mon, 06 Apr 2026 15:40:28 GMT 2026-04-06T15:40:28Z https://idr.niser.ac.in/jspui/handle/123456789/1128 Title: Computational immunology: applications Authors: Ghosh, Shyamasree Description: Computational Immunology: Applications focuses on different mathematical models, statistical　tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including　 Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing　 Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system Wed, 05 Feb 2020 00:00:00 GMT https://idr.niser.ac.in/jspui/handle/123456789/1128 2020-02-05T00:00:00Z https://idr.niser.ac.in/jspui/handle/123456789/1127 Title: Clinical significance of C-reactive protein Authors: Ghosh, Shyamasree Abstract: This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology. Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel disease, and the expression of CRP in pediatric respiratory diseases. In addition it discusses the clinical role of CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients, and also as a primary marker for inflammation. Given its scope, this book will appeal to scholars in various fields of medicine and biology. Fri, 18 Dec 2020 00:00:00 GMT https://idr.niser.ac.in/jspui/handle/123456789/1127 2020-12-18T00:00:00Z https://idr.niser.ac.in/jspui/handle/123456789/1126 Title: Sialic acids and sialoglycoconjugates in the biology of life, health and disease Authors: Ghosh, Shyamasree Description: Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Wed, 08 Jan 2020 00:00:00 GMT https://idr.niser.ac.in/jspui/handle/123456789/1126 2020-01-08T00:00:00Z https://idr.niser.ac.in/jspui/handle/123456789/1124 Title: Stem cells: biology and therapeutics Authors: Ghosh, Shyamasree Abstract: Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences. Sun, 25 Jul 2021 00:00:00 GMT https://idr.niser.ac.in/jspui/handle/123456789/1124 2021-07-25T00:00:00Z